Concentration determination in a diffusion barrier layer

摘要

The present invention relates to improved electrochemical biosensor strips and methods for determining the concentration of an analyte in a sample. By selectively measuring a measurable species residing in a diffusion barrier layer, to the substantial exclusion of the measurable species residing exterior to the diffusion barrier layer, measurement errors introduced by sample constituents, such as red blood cells, and manufacturing variances may be reduced.

主权项

1. An electrochemical sensor strip, comprising:
a base; a first electrode on the base, the first electrode having a first layer on a first conductor, the first layer including a reagent layer and a second layer between the first conductor and the first layer, the second layer comprising an at least partially water-soluble polymeric material; and a second electrode on the base.