Compositions and methods for encapsulating vaccines for the oral vaccination and boostering of fish and other animals

摘要

A composition comprising a drug or pharmaceutically active agent and a bioadhesive delivery system provides for the oral delivery of a vaccine to animals, particularly aquatic animals.

主权项

1. A composition for oral delivery, comprising one or more drugs constituting in total from about 0.05% to about 10% w/w of the composition, one or more bioadhesive polymers selected from the group consisting of chitosan, dimethyl chitosan, trimethyl chitosan, carboxymethyl chitosan, hyaluronic acid, gum Karaya, cationic guar and mixtures thereof and constituting in total from about 0.05% to about 10% w/w of the composition, and one or more short chain polysaccharides or oligosaccharides constituting in total from about 0.05% to about 30% w/w of the composition, wherein the composition is a crosslinked solid;
wherein the composition further comprises one or more adjuvant compounds.