发明名称 |
Method for treating virus infection using derivative of aniline |
摘要 |
A method for treating a virus infection in a subject is provided. The method comprising administering to the subject in need an effective amount of a derivative of aniline selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound of formula (I), a pharmaceutically acceptable ester of the compound of formula (I), and combinations thereof:;wherein,R1 is C1 to C10 alkyl;R2 is H or C1 to C4 alkyl; andR3, R4, R5, R6 and R7 are independently H, —OH, halogen, C1 to C10 alkyl, C1 to C10 alkoxyl, or (C1 to C10 alkylene)-O—O—(C1 to C10 alkyl). |
申请公布号 |
US9205073(B2) |
申请公布日期 |
2015.12.08 |
申请号 |
US201414263591 |
申请日期 |
2014.04.28 |
申请人 |
CHINA MEDICAL UNIVERSITY |
发明人 |
Lin Cheng-Wen;Huang An-Cheng;Lien Jin-Cherng;Ping Jia-Fong;Li Shih-Wen;Chen I-Chieh |
分类号 |
A61K31/34;A61K38/00;A61K31/341;A61K38/21 |
主分类号 |
A61K31/34 |
代理机构 |
Andrews Kurth LLP |
代理人 |
Wang Ping;Andrews Kurth LLP |
主权项 |
1. A method for treating a virus infection in a subject, comprising administering to the subject in need an effective amount of a derivative of aniline selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound of formula (I) combinations thereof: wherein, R1 is C1 to C6 alkyl; R2 is H; R3, R5, and R7 are independently H, or halogen; R4 and R6 are independently H, halogen, or C1 to C4 alkyl; and the virus is at least one of Flavivirus genus virus and Enterovirus genus virus. |
地址 |
Taichung TW |