发明名称 |
Adhesive skin patch containing serotonin receptor antagonist drug |
摘要 |
Provided is a transdermal absorption-type patch containing a serotonin receptor antagonist, which has a short transdermal absorption delay time (lag time), and in which the maximum transdermal permeation rate of the drug can be reached within a short time and the drug can disappear from circulating blood rapidly. That is, provided is a patch containing a serotonin receptor antagonist, wherein the patch contains an adhesive layer comprising a non-functional acrylic adhesive, a water-soluble organic amine, a fatty acid ester, and a serotonin receptor antagonist such as granisetron as an active ingredient. |
申请公布号 |
US9205060(B2) |
申请公布日期 |
2015.12.08 |
申请号 |
US201214130385 |
申请日期 |
2012.07.04 |
申请人 |
Teikoku Seiyaku Co., Ltd. |
发明人 |
Kamakura Takashi;Takano Daiki |
分类号 |
A61K9/70;A61K47/14;A61K47/18;A61K47/32;A61K31/4178;A61K31/4184;A61K31/439 |
主分类号 |
A61K9/70 |
代理机构 |
Wenderoth, Lind & Ponack, L.L.P. |
代理人 |
Wenderoth, Lind & Ponack, L.L.P. |
主权项 |
1. A patch containing a serotonin receptor antagonist, wherein the patch contains an adhesive layer comprising a non-functional acrylic adhesive, 1-10% by weight of a water-soluble organic amine, 2-20% by weight of a fatty acid ester, and a serotonin receptor antagonist as an active ingredient wherein the patch does not contain lauric acid diethanolamide. |
地址 |
Kagawa JP |