| 发明名称 |
SYNTHESIS OF QUATERNARY SALT COMPOUNDS |
| 摘要 |
<p>A multistep process for preparing quaternary chloride compounds that are antagonists to CCR2 and having the Formula (I) is provided, in which the final stage is conversion of a tertiary amine directly into a quaternary chloride salt under pressure and at an elevated temperature. (see formula I)</p> |
| 申请公布号 |
CA2703717(C) |
申请公布日期 |
2015.12.08 |
| 申请号 |
CA20082703717 |
申请日期 |
2008.10.23 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
LI, XUN |
| 分类号 |
C07D309/14;C07C231/00;C07D207/14;C07D211/56;C07D295/00;C07D307/22;C07D333/36;C07D335/02 |
主分类号 |
C07D309/14 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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