发明名称 |
PROCESS FOR PREPARING NUCLEOSIDE PRODRUGS. |
摘要 |
A process for preparing phosphoramidates of nucleosides where a desired enantiomer, having regard to the asymmetric chiral centre of the phosphorus atom P, is provided in an enriched amount. The process comprises admixing a nucleoside with a phosphorochloridate in the presence of a catalyst comprising a metal salt selected from the group consisting of salts of Ciu Fe, La and Yb. |
申请公布号 |
MX2015006195(A) |
申请公布日期 |
2015.12.08 |
申请号 |
MX20150006195 |
申请日期 |
2013.11.15 |
申请人 |
UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED |
发明人 |
MCGUIGAN, CHRISTOPHER;PERTUSATI, FABRIZIO |
分类号 |
C07H1/00;C07H19/06;C07H19/16 |
主分类号 |
C07H1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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