发明名称 CYCLOPROPANE COMPOUNDS
摘要 <p>A cyclopropane compound represented by the following formula (A) or a pharmaceutically acceptable salt thereof has orexin receptor antagonism, and therefore has a potential use for the treatment of sleep disorder for which orexin receptor antagonism is effective, for example, insomnia: (see formula A) wherein Q represents -CH- or a nitrogen atom, R1a and R1b each independently represent a C1-6 alkyl group and the like, R1c represents a hydrogen atom and the like, R2a, R2b, R2c and R2d each independently represent a hydrogen atom, a halogen atom, a C1-6 alkyl group and the like, R3a, R3b and R3c each independently represent a hydrogen atom, a halogen atom and the like, and R3d represents a hydrogen atom and the like.</p>
申请公布号 CA2811895(C) 申请公布日期 2015.12.08
申请号 CA20112811895 申请日期 2011.09.20
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 TERAUCHI, TARO;TAKEMURA, AYUMI;DOKO, TAKASHI;YOSHIDA, YU;TANAKA, TOSHIAKI;SORIMACHI, KEIICHI;NAOE, YOSHIMITSU;BEUCKMANN, CARSTEN;KAZUTA, YUJI
分类号 C07D239/34;A61K31/505;A61K31/506;A61K31/517;A61K31/538;A61P1/14;A61P3/10;A61P11/00;A61P13/08;A61P25/00;A61P25/04;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P25/36;C07D239/47;C07D239/88;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D409/14;C07D413/12;C07D417/12;C07D471/04 主分类号 C07D239/34
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