发明名称 Pyrazole tetrahydronaphthyl carboxamides
摘要 The present invention relates to novel pyrazole(thio)tetrahydronaphthyl carboxamides, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials.
申请公布号 US9204646(B2) 申请公布日期 2015.12.08
申请号 US201314399544 申请日期 2013.05.06
申请人 BAYER CROPSCIENCE AG 发明人 Maechling Simon;Es-Sayed Mazen;Dahmen Peter;Wachendorff-Neumann Ulrike;Bernier David;Carles Lionel;Dubost Christophe;Vors Jean-Pierre;Brunet Stephane;Lachaise Helene
分类号 A01N43/56;C07D231/14;C07D231/16;C07C211/60;C07C251/50 主分类号 A01N43/56
代理机构 Miles & Stockbridge PC 代理人 Miles & Stockbridge PC
主权项 1. A 1-Methyl-3-dihalogenomethyl-5-halogenopyrazole(thio)tetrahydronaphthyl carboxamide compound of formula (I) in which Hal1 represents chlorine or fluorine; Hal2 represents chlorine or fluorine; T represents an oxygen or sulfur atom; Q represents hydrogen, C1-C6-alkylsulfonyl, C1-C4-alkoxy-C1-C4-alkyl, C1-C4-haloalkylsulfonyl, halo-C1-C4-alkoxy-C1-C4-alkyl; X represents halogen, nitro, cyano, C1-C12-alkyl; C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms; C1-C6-alkoxy; C1-C6-haloalkoxy having 1 to 9 identical or different halogen atoms; C1-C6-alkylsulfanyl; C1-C6-haloalkylsulfanyl having 1 to 9 identical or different halogen atoms; C1-C6-alkylsulfonyl; C1-C6-haloalkylsulfonyl having 1 to 9 identical or different halogen atoms; C2-C12-alkenyl; C2-C12-alkynyl; C3-C7-cycloalkyl; phenyl; tri(C1-C8)alkylsilyl; tri(C1-C8)alkylsilyl-C1-C8-alkyl; m represents 0, 1, 2 or 3 R1, R2, R3, R4, R5, R6, R7 and R8 independently one to another represent hydrogen; halogen; cyano; C1-C16-alkyl; C2-C16-haloalkyl having 1 to 9 identical or different halogen atoms; C3-C8-cycloalkyl; C3-C7-halocycloalkyl having 1 to 9 identical or different halogen atoms; C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms; (C3-C8-cycloalkyl)-C1-C8-alkyl; (C3-C8-cycloalkyl)-C3-C8-cycloalkyl; C2-C16-alkenyl; C2-C16-alkynyl; C2-C16-alkenyl-C1-C16-alkyl; C2-C16-alkynyl-C1-C16-alkyl; C1-C16-alkoxy; C3-C8-cycloalkyloxy; (C3-C8-cycloalkyl)-C1-C8-alkyloxy; C1-C8-alkylsulfanyl; C3-C8-cycloalkylsulfanyl; (C3-C8-cycloalkyl)-C1-C8-alkylsulfanyl; C2-C16-alkenyloxy; C3-C8-alkynyloxy; aryl-C1-C8-alkyloxy which is optionally substituted by up to 6 identical or different groups Rb; aryl-C1-C8-alkylsulfanyl which is optionally substituted by up to 6 identical or different groups Rb; aryloxy which is optionally substituted by up to 6 identical or different groups Rb; arylsulfanyl which is optionally substituted by up to 6 identical or different groups Rb; (C3-C8-cycloalkyl)-C2-C8-alkenyl; (C3-C8-cycloalkyl)-C2-C8-alkynyl; tri(C1-C8)alkylsilyl; tri(C1-C8)alkylsilyl-C1-C8-alkyl; aryl-C1-C8-alkyl which is optionally substituted by up to 6 identical or different groups Rb; aryl-C2-C8-alkenyl which is optionally substituted by up to 6 identical or different groups Rb; aryl-C2-C8-alkynyl which is optionally substituted by up to 6 identical or different groups Rb; C1-C8-alkylamino; di-C1-C8-alkylamino; arylamino which is optionally substituted by up to 6 identical or different groups Rb; C1-C8-alkylcarbonyl; C1-C8-alkylcarbonyloxy; C1-C8-alkylcarbonylamino; C1-C8-alkoxycarbonyl; C1-C8-alkyloxycarbonyloxy; C1-C8-alkylcarbamoyl; di-C1-C8-alkylcarbamoyl; C1-C8-alkylaminocarbonyloxy; di-C1-C8-alkylaminocarbonyloxy; N—(C1-C8-alkyl)hydroxycarbamoyl; C1-C8-alkoxycarbamoyl; N—(C1-C8-alkyl)-C1-C8-alkoxycarbamoyl; aryl-C1-C8-alkylamino which is optionally substituted by up to 6 identical or different groups Rb; (C1-C8-alkoxyimino)-C1-C8-alkyl; (C2-C8-cycloalkoxyimino)-C1-C8-alkyl; C1-C8-alkyliminoxy; C1-C8-alkyliminoxy-C1-C8-alkyl; each of which is optionally substituted; provided that R1, R2, R3, R4, R5, R6 and R7 do not represent hydrogen at the same time when R8 represents hydrogen or trifluoromethyl; R1 and R2 can form together with the carbon to which they are attached a C3-C8-cycloalkyl; C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle; each of which is optionally substituted; or may represent a group ═C(Y1)Y2 or a group ═N—O—Rc; R3 and R4 can form together with the carbon to which they are attached a C3-C8-cycloalkyl; C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle; each of which is optionally substituted; or may represent a group ═C(Y1)Y2 or a group ═N—O—Rc; R5 and R6 can form together with the carbon to which they are attached a C3-C8-cycloalkyl; C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle; each of which is optionally substituted; or may represent a group ═C(Y1)Y2 or a group ═N—O—Rc; R7 and R8 can form together with the carbon to which they are attached a C3-C8-cycloalkyl; C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle; each of which is optionally substituted; or may represent a group ═C(Y1)Y2 or a group ═N—O—Rc; R1 and R3 or R3 and R5 or R5 and R7 can form with the carbons to which they are attached a C3-C8-cycloalkyl; C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle; each of which is optionally substituted; Rb represents halogen; nitro, cyano, C1-C12-alkyl; C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms; C1-C6-alkoxy; C1-C6-haloalkoxy having 1 to 9 identical or different halogen atoms; C1-C6-alkylsulfanyl; C1-C6-haloalkylsulfanyl having 1 to 9 identical or different halogen atoms; C1-C6-alkylsulfonyl; C1-C6-haloalkylsulfonyl having 1 to 9 identical or different halogen atoms; C2-C12-alkenyl; C2-C12-alkynyl; C3-C7-cycloalkyl; phenyl; tri(C1-C8)alkylsilyl; tri(C1-C8)alkylsilyl-C1-C8-alkyl; Y1 and Y2 independently of one another represent hydrogen, halogen, C1-C12-alkyl; C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms; C1-C8-alkylsulfanyl; phenyl; each of which is optionally substituted; or Y1 and Y2 can form together with the carbon to which they are attached a C3-C8-cycloalkyl or a C3-C8-cycloalkenyl or a saturated 5, 6 or 7 membered heterocycle; each of which is optionally substituted; Rc represents C1-C16-alkyl; C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms; C3-C8-cycloalkyl; (C3-C8-cycloalkyl)-C1-C8-alkyl; (C3-C8-cycloalkyl)-C3-C8-cycloalkyl; C2-C8-alkenyl-C1-C16-alkyl; C2-C8-alkynyl-C1-C16-alkyl; aryl-C1-C8-alkyl which is optionally substituted by up to 6 identical or different groups Rb; each of which is optionally substituted.
地址 Monheim DE