The present invention relates to: an insulin analog, wherein the insulin titer is reduced compared with a natural form and the binding force to an insulin receptor is reduced in order to increase the half-life of insulin in the blood; a conjugate, wherein the insulin analog and a carrier are connected; an extended release preparation containing the conjugate; and a method for preparing the conjugate.
申请公布号
PH12015501814(A1)
申请公布日期
2015.12.07
申请号
PH2014120155018
申请日期
2015.08.18
申请人
HANMI PHARM. CO., LTD.
发明人
HWANG, SANG YOUN;HUH, YONG HO;KIM, JIN YOUNG;HONG, SUNG HEE;CHOI, IN YOUNG;JUNG, SUNG YOUB;KWON, SE CHANG;KIM, DAE JIN;KIM, HYUN UK;JANG, MYUNG HYUN;KIM, SEUNG SU