发明名称 |
NANOPARTICLE DRUG CONJUGATES |
摘要 |
Described herein are nanoparticle drug conjugates (NDCs), which, in certain embodiments, comprise a non-toxic, multi-modality, clinically proven silica-based nanoparticle platform with covalently attached drug molecules/moieties. The nanoparticle drug conjugates (NDCs) demonstrate imaging capability and targeting ligands which efficiently clear through the kidneys. Furthermore, the conjugates incorporate therapeutic agents for cancer detection, prevention, and/or treatment. |
申请公布号 |
CA2947895(A1) |
申请公布日期 |
2015.12.03 |
申请号 |
CA20152947895 |
申请日期 |
2015.05.27 |
申请人 |
MEMORIAL SLOAN KETTERING CANCER RESEARCH;CORNELL UNIVERSITY |
发明人 |
YOO, BARNEY;BRADBURY, MICHELLE S.;WIESNER, ULRICH;MA, KAI |
分类号 |
A61K9/14;A61K31/506;A61K31/517;B82Y5/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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