DUAL CHAMBER MIXING SYRINGES AND METHODS OF USING SAME

摘要

Provided are mixing syringes having two chambers defined by a pair of pistons located one above the other inside the syringe. Mixing of components separately stored in each of the two chambers occurs when a reversible valve occluding a bore in the distal piston near the discharge end is unseated by removing the retention sleeve and pressing the knob, and the proximal piston nearer the top of the syringe is moved axially toward the distal piston. Further movement of the proximal piston causes it to abut the distal piston resulting in the two pistons acting as one to dispel the now mixed components through the discharge end. Methods are provided for using the syringes for storage and mixing components; discharging the components from the syringe such as by administering the components to a patient in need thereof through a needle when the components are a medicament product.

主权项

1. A dual-chamber, mixing syringe, comprising:
a. a hollow body having inner walls, a distal discharge end, and a proximal piston-rod receiving end; b. a piston rod extending into the hollow body through an opening in the piston-rod receiving end; c. an axially-bored first piston and a second piston, each piston is positioned inside the hollow body in slidable, fluid-tight engagement with the inner walls of the hollow body, wherein:
i. the first piston is positioned nearer the discharge end than the second piston;ii. the first piston together with the inner walls of the hollow body and the discharge end of the hollow body define a distal chamber;iii. the second piston together with the first piston and inner walls of the hollow body define a proximal chamber; and,iv. the second piston is in actuating engagement with the piston rod such that the second piston moves axially toward the discharge end when the piston rod is depressed; and, d. a valve for reversibly sealing the axial bore in the first piston.