发明名称 |
Novel EPID dosimetry method and system for radiation therapy |
摘要 |
A method of electronic portal imaging (EPID) for radiation dosimetric measurement and quality assurance (QA) in radiation therapy is provided that includes imaging a calibration photon beam and a treatment beam using an EPID imager disposed between a plastic water build-up phantom and a plastic water back-scatter phantom that is thicker than the plastic water build-up phantom, correcting the EPID images using an off-axis correction map that takes into account a horn-shape of a photon fluence profile, deconvolving the corrected EPID images using a Monte Carlo simulated EPID response kernel, the deconvolved corrected EPID images provide a primary photon fluence map, reconstructing a relative dose map using the primary photon fluence map convolving with a Monte Carlo simulated pencil-beam dose distribution kernel, and generating an absolute dose map using cross calibration to a 10x10 cm2 square field that is compared with a planned dose distribution for QA analysis. |
申请公布号 |
US2015343241(A1) |
申请公布日期 |
2015.12.03 |
申请号 |
US201414760324 |
申请日期 |
2014.01.13 |
申请人 |
The Board of Trustees of the Leland Stanford Junior University |
发明人 |
Han Bin;Xing Lei |
分类号 |
A61N5/10;G06T5/00 |
主分类号 |
A61N5/10 |
代理机构 |
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代理人 |
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主权项 |
1. A method of electronic portal imaging (EPID) for radiation dosimetric measurement and quality assurance (QA) in radiation therapy, comprising:
a. imaging a calibration photon beam and a treatment beam using an EPID imager, wherein said EPID imager is disposed between a plastic water build-up phantom and a plastic water back-scatter phantom, wherein said plastic water back-scatter phantom is thicker than said plastic water build-up phantom; b. correcting said EPID images using an off-axis correction map, wherein said off-axis correction takes into account a horn-shape of a photon fluence profile; c. deconvolving said corrected EPID images using a Monte Carlo simulated EPID response kernel, wherein said deconvolved corrected EPID images provide a primary photon fluence map; d. reconstructing a relative dose map using said primary photon fluence map convolving with a Monte Carlo simulated pencil-beam dose distribution kernel; and e. generating an absolute dose map using cross calibration to a 10×10 cm2 square field, wherein said absolute dose map is compared with a planned dose distribution for QA analysis. |
地址 |
Palo Alto CA US |