| 发明名称 |
COMPOSITIONS AND METHODS FOR IN VIVO IMAGING |
| 摘要 |
The present disclosure provides lipid-probe compounds, and compositions comprising the compounds. A subject lipid-probe compound is useful for various imaging applications, which are also provided. |
| 申请公布号 |
US2015343094(A1) |
申请公布日期 |
2015.12.03 |
| 申请号 |
US201514806207 |
申请日期 |
2015.07.22 |
| 申请人 |
The Regents of the University of California |
发明人 |
Bertozzi Carolyn Ruth;Stahl Andreas;Henkin Amy Helene;Dubikovskaya Elena A.;Cohen Allison |
| 分类号 |
A61K49/00;C12Q1/66;C07D277/64;C07D257/02;A61K51/04 |
主分类号 |
A61K49/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of the formula:
Q-L-X—Y wherein Q is a lipid; X is an optional leaving group (e.g., O, S, or NH); L is a cleavable linker comprising a cleavable bond that provides for release of Y or X—Y following cleavage of the linker; and Y comprises a detectable moiety that, after release, generates a direct or indirect detectable signal. |
| 地址 |
Oakland CA US |
