| 摘要 |
Disclosed herein are antisense compounds and methods for decreasing SOD-1 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate SOD-1 associated diseases, disorders, and conditions. Such SOD-1 associated diseases include amyotrophic sclerosis (ALS). |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
SWAYZE, ERIC, E.;COLE, TRACY;KORDASIEWICZ, HOLLY;FREIER, SUSAN, M.;CONDON, THOMAS, P.;WANCEWICZ, EDWARD;LOCKHART, TRISHA;VICKERS, TIMOTHY;SINGH, PRIYAM |
