IRE-1α INHIBITORS

摘要

PROBLEM TO BE SOLVED: To provide compounds which directly inhibit inositol requiring enzyme 1 (IRE-1α activity) in vitro, prodrugs, and pharmaceutically acceptable salts thereof.SOLUTION: The present invention provides a compound represented by formula (A) [Rand Rare H or the like; Q-Q, together with the benzene ring to which they are attached, form a benzofused ring, where at least one of Q-Qis a heteroatom selected from N, O, and S.