| 发明名称 |
Retinal OFF circuit-specific promoter |
| 摘要 |
The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in cones and/or OFF bipolar cells of a gene when operatively linked to a nucleic acid sequence coding for said gene. |
| 申请公布号 |
US2015344907(A1) |
申请公布日期 |
2015.12.03 |
| 申请号 |
US201314421632 |
申请日期 |
2013.08.26 |
| 申请人 |
ROSKA Botond;JUETTNER Josephine |
发明人 |
Roska Botond;Juettner Josephine |
| 分类号 |
C12N15/85;C07K14/705;A61K48/00 |
主分类号 |
C12N15/85 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated nucleic acid molecule comprising, a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression of a gene in cones and/or OFF bipolar cells when a nucleic acid sequence coding for said gene is operatively linked to said isolated nucleic acid molecule. |
| 地址 |
Bael CH |
