发明名称 |
THERAPEUTIC TRATMENT OF SKIN DISEASE WITH RECOMBINANT COMMENSAL SKIN MICROORGANISMS |
摘要 |
The invention relates to methods for treating or preventing abnormal skin conditions in a human in need thereof, comprising administering a cell culture composition comprising a living culture of bacteria comprising at least one engineered strain that produces a recombinant polypeptide for therapeutic treatment of the abnormal skin condition. The invention also relates to pharmaceutical compositions containing, as the active principle, engineered microorganisms expressing non-vaccinogenic pharmacologically active recombinant therapeutic polypeptides in order to treat or prevent abnormal skin conditions. |
申请公布号 |
WO2015184134(A1) |
申请公布日期 |
2015.12.03 |
申请号 |
WO2015US32972 |
申请日期 |
2015.05.28 |
申请人 |
AZITRA |
发明人 |
MUNIVAR, AZIM, MOMIN;WHITFILL, TRAVIS, MICHAEL |
分类号 |
A61K38/17;A61K8/64;A61K8/99;A61K9/06;A61K35/74;A61K38/16;A61P17/00;C07K19/00 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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