发明名称 |
Double-acylated GLP-1 derivatives |
摘要 |
The invention relates to a derivative of a GLP-1 analogue, which analogue comprises a first K residue at a position corresponding to position 27 of GLP-1(7-37) (SEQ ID NO: 1 ); a second K residue at a position corresponding to position T of GLP-1(7-37), where T is an integer in the range of 7-37 except 18 and 27; and a maximum of ten amino acid changes as compared to GLP-1(7-37); wherein the first K residue is designated K |
申请公布号 |
AU2012241894(B2) |
申请公布日期 |
2015.12.03 |
申请号 |
AU20120241894 |
申请日期 |
2012.04.12 |
申请人 |
NOVO NORDISK A/S |
发明人 |
WIECZOREK, BIRGIT;SPETZLER, JANE;KRUSE, THOMAS;LINDEROTH, LARS;KOFOED, JACOB |
分类号 |
C07K14/065;A01N43/90;A01N61/00;A01P3/00;A61K38/26 |
主分类号 |
C07K14/065 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|