SYSTEM AND METHODS FOR TREATING ATRIAL FIBRILLATION USING HEMODYNAMIC RESPONSES

摘要

Systems and methods for treating atrial tachyarrhythmias such as atrial fibrillation (AF) are disclosed. By monitoring a patient's hemodynamic sensor response to a candidate AF therapy, the present systems and methods can be used to determine an individualized AF therapy leading to a desirable hemodynamic outcome. A medical system can include one or more programmable therapy circuits and a hemodynamic sensor circuit. The system includes a therapy selection circuit that automatically programs and sequentially delivers at least a first candidate therapy and a different second candidate therapy. By comparing the values of a hemodynamic parameter in response to or during the first candidate therapy to that in response to or during the second candidate therapy, a desired AF therapy can be determined as the candidate therapy that leads to faster or more significant hemodynamic recovery.

主权项

1. A medical system, comprising:
an atrial fibrillation (AF) detection circuit configured to detect an atrial fibrillation (AF) in a patient; one or more programmable therapy circuits configured to generate and deliver to the patient a respective therapy in response to the detection of the AF event; a hemodynamic sensor circuit configured to sense a hemodynamic status output indicative of a hemodynamic status of the patient; and a therapy selection circuit coupled to the hemodynamic sensor circuit and the one or more programmable therapy circuits, the therapy selection circuit configured to:
in response to the detection of the AF event, automatically program the one or more programmable therapy circuits to generate and sequentially deliver to the patient a first candidate therapy and a different second candidate therapy;receive from the hemodynamic sensor circuit a first value of the hemodynamic status output in response to or during the delivery of the first candidate therapy and a second value of the hemodynamic status output in response to or during the delivery of the second candidate therapy; andselect a desired therapy based on the first and second values of the hemodynamic status output.