发明名称 COMBINATION
摘要 The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering 2-methyl-1-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylic acid, or a pharmaceutically acceptable salt thereof, andN-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)6,8-dimethy;-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide, or a pharmaceutically acceptable salt or solvate thereof, to a human in need thereof.
申请公布号 US2015342957(A1) 申请公布日期 2015.12.03
申请号 US201414759314 申请日期 2014.01.08
申请人 GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED 发明人 BACHMAN Kurtis Earl;GRESHOCK Joel David;HARDWICKE Mary Ann
分类号 A61K31/5377;A61K31/519 主分类号 A61K31/5377
代理机构 代理人
主权项 1. A combination comprising: (i) a compound of Structure (I): or a pharmaceutically acceptable salt thereof; and (ii) a compound of Structure (II): or a pharmaceutically acceptable salt or solvate thereof.
地址 Brentford Middlesex GB