DRUG DELIVERY SYSTEMS AND RELATED METHODS OF USE

摘要

The present disclosure relates generally to drug delivery systems and related methods of use. The drug delivery systems can include one or more particles, each of which can include a biologically active compound dispersed therein. The drug delivery systems can also be configured to exhibit zero-order or near-zero-order release of the biologically active compound. The particles can be cylindrical or rod-like in shape, and can include a polymeric inner matrix having a biologically active compound dispersed therein, and a polymeric outer layer disposed at least partially around the inner matrix.

主权项

1. A drug delivery system, comprising:
an implantable or injectable biocompatible particle, comprising:
a polymeric inner matrix comprising a biologically active compound; anda polymeric outer layer disposed at least partially around the inner matrix, the polymeric outer layer being substantially impermeable to the biologically active compound,wherein the particle is configured to exhibit zero-order or near-zero-order release of the biologically active compound.