发明名称 |
CREATION OF THREE-DIMENSIONAL ARTIFICIAL TISSUE FROM PLURIPOTENT STEM CELL-DERIVED CELLS, AND OSTEOCHONDRAL REGENERATION TREATMENT USING SAID ARTIFICIAL TISSUE |
摘要 |
Provided are an improved three-dimensional synthetic tissue, a composite tissue thereof, and a production method of the same. The present invention provides : an implantable synthetic tissue substantially made of a mesenchymal stem cell induced from a pluripotent stem cell or an equivalent cell thereof, and an extracellular matrix derived from the cell; a composite tissue for treating or preventing a disease, disorder, or condition associated with an osteochondral defect, comprising a synthetic tissue and an artificial bone, wherein the artificial bone is smaller in size than a depth of a defect of a bone section in the osteochondral defect; and a production method of the same. |
申请公布号 |
EP2949747(A1) |
申请公布日期 |
2015.12.02 |
申请号 |
EP20140743709 |
申请日期 |
2014.01.24 |
申请人 |
OSAKA UNIVERSITY |
发明人 |
YOSHIKAWA,HIDEKI;NAKAMURA, NORIMASA;SHIMOMURA, KAZUNORI;MORIGUCHI, YU;CHIJIMATSU, RYOTA;YASUI, YUKIHIKO |
分类号 |
C12N5/071;A61L27/00;C12N5/0775 |
主分类号 |
C12N5/071 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|