发明名称 |
METHOD OF MONITORING GENOMIC INSTABILITY USING 3D MICROSCOPY AND ANALYSIS |
摘要 |
<p>The present invention relates to a method of detecting and monitoring genomic instability in a cell using three-dimensional analysis to assess telomeric and/or chromosomal organization. In addition, the invention relates to a method and system for characterizing the 3D organization of telomeres and/or chromosomes. The system includes an input module for inputting image data of the 3D organization of telomeres and/or chromosomes and a characteristic module for finding a parameter of the 3D organization. The invention also relates to the use of the three-dimensional analysis to detect, diagnose or monitor disease, particularly proliferative diseases such as cancer.</p> |
申请公布号 |
EP1594990(B1) |
申请公布日期 |
2015.12.02 |
申请号 |
EP20040713499 |
申请日期 |
2004.02.23 |
申请人 |
3D SIGNATURES INC. |
发明人 |
MAI, SABINE;CHUANG, TONY, CHIH, YUAN;MOSHIR, SHARAREH;GARINI, YUVAL;VERMOLEN, BARTHOLOMEUS J. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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