发明名称 |
生物学的サンプルろ過中の超音波、逆流洗浄、およびフィルタ運動によるフィルタ洗浄装置および方法 |
摘要 |
The present application is directed to the separation of—a solid fraction from a fluid sample particularly a therapeutic cellular fraction from a biological sample such as a bone marrow sample by a porous filter (2) which separates a filtration unit (1) into an upper pre-filtration chamber (3) into which a fluid sample (4) requiring cell separation is introduced and a lower post-filtration chamber (5) into which a fluid (6) capable of transmitting an acoustic standing wave is introduced. An acoustic element (8) is coupled to a substrate (7) which is located within and at the bottom of the lower chamber (5) and which resonates in response to the acoustic generating element (8) and generates a standing wave through the two fluid phases and the filter to agitate the sample (4). Simultaneously, a cyclic process of vacuum draw (9). causes movement of the sample (4) downwards through the filter (2). Vacuum pressure, fluid flow rate and frequency of vibration are controlled from a remote unit housing appropriate pumps and valves. |
申请公布号 |
JP5827971(B2) |
申请公布日期 |
2015.12.02 |
申请号 |
JP20130078465 |
申请日期 |
2013.04.04 |
申请人 |
スミス アンド ネフュー ピーエルシーSMITH & NEPHEW PUBLIC LIMITED COMPANY |
发明人 |
スティーヴン・カラン |
分类号 |
C12M1/26;B01D33/15;B01D35/20;C12M1/12 |
主分类号 |
C12M1/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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