发明名称 ASTER GLEHNI FRACTIONS OR COMPOUNDS ISOLATED THEREFROM HAVING ANTI-INFLAMMATORY ACTIVITY
摘要 The present invention relates to an Aster glehni fraction having excellent anti-inflammatory activity and an active compound isolated therefrom. The present invention provides an ethyl acetate fraction of Aster glehni and an active compound isolated from the fraction, where 6′-O-caffeoylroseoside, 6′-O-caffeoyldihydrosyringin and glehnoside have an antioxidant effect due to a strong free radical scavenging ability and simultaneously inhibit generation of pro-inflammatory cytokines such as nitric oxide (NO), prostaglandin E2 (PGE2), tumour necrosis factor alpha (TNF-α), interleukin-6 (IL-6), and interleukin-1beta (IL-1β) which are inflammatory metabolite induced by lipopolysaccharide (LPS), thereby being usefully used as an active component of medicines, cosmetics and health foods needed in treating, preventing and improving inflammatory diseases.
申请公布号 KR20150135036(A) 申请公布日期 2015.12.02
申请号 KR20140121177 申请日期 2014.09.12
申请人 KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 发明人 KIM, HYOUNG JA;JIN, CHANG BAE;SON, MIN JEOUNG;LEE, YONG SUP;YOOK, CHANG SOO;LEE, KYUNG TAE;LEE, JAE YEOL
分类号 A61K31/7034;A61K36/28;A61P29/00 主分类号 A61K31/7034
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