发明名称 MANUFACTURING PROCESS FOR MEMANTINE
摘要 A method for manufacturing 3,5-dimethyl-1-adamantanamine of the present invention comprises: (i) a step of reacting 3,5-dimethyl-1-adamantanol with an acid and nitrile in an organic solvent to obtain a reaction solution; (ii) a step of adding water to the reaction solution obtained in step (i) to obtain 1-amido-3,5-dimethyladamantane; and (iii) a step of hydrolyzing 1-amido-3,5-dimethyladamantane obtained in step (ii) in the presence of an alcohol-containing solvent and an inorganic base.
申请公布号 EP2949643(A1) 申请公布日期 2015.12.02
申请号 EP20140743873 申请日期 2014.01.16
申请人 MITSUBISHI GAS CHEMICAL COMPANY, INC. 发明人 SHIMO, TETSUYA
分类号 C07C209/62;C07C211/38;C07C231/06;C07C233/06 主分类号 C07C209/62
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