发明名称 |
Random pentapolymer for treatment of autoimmune diseases |
摘要 |
The present invention relates to a synthetic polypeptide which is a random linear pentapolymer comprising alanine, glutamic acid, lysine, tyrosine and phenylalanine and use thereof in treating autoimmune diseases, in particular multiple sclerosis. |
申请公布号 |
US9200114(B2) |
申请公布日期 |
2015.12.01 |
申请号 |
US201313764460 |
申请日期 |
2013.02.11 |
申请人 |
MAPI PHARMA LTD. |
发明人 |
Marom Ehud;Rubnov Shai |
分类号 |
A61K38/02;A61K38/16;C08G69/10;C07K14/00;A61K31/785;A61K45/06;A61K38/00 |
主分类号 |
A61K38/02 |
代理机构 |
Rothwell, Figg, Ernst & Manbeck, P.C. |
代理人 |
Rothwell, Figg, Ernst & Manbeck, P.C. |
主权项 |
1. A pentapolymer or a salt thereof, which is a linear random copolymer of alanine, glutamic acid, lysine, tyrosine and phenylalanine, wherein the molar ratio of alanine to glutamic acid to lysine to tyrosine to phenylalanine is about 2.5:1.9:4.5:1.0:0.9, respectively. |
地址 |
Ness Ziona IL |