Method of treating or preventing thrombosis in a patient with 5-HT2A receptor antagonist thromboserin

摘要

There is provided the use of a 5-HT2A receptor antagonist to treat or prevent thrombosis, particularly arterial thrombosis, in a human or animal patient. The patient is suitably one who is at risk of bleeding, particularly those about to undergo, or those undergoing, surgery. A preferred 5-HT2A antagonist is thromboserin.

主权项

1. A method comprising administering pre-operatively, during a surgical operation, or post-operatively an amount ranging from about 20 mg to about 100 mg daily of a 5-HT2A receptor antagonist comprising thromboserin or a pharmaceutically acceptable salt thereof to treat or prevent thrombosis in a human or animal patient characterized in that administration results in a statistically insignificant variation in bleeding time during surgery.