Injectable solution containing therapeutic agent for osteoarthritis

摘要

Injections for treating and preventing diseases classified as any of grade 1 to 3 according to the ICRS classification of osteoarthritis, diseases classified as any of grade 1 to 3 according to the Kellgren-Lawrence classification of osteoarthritis or diseases classified as any of grade 1 to 3 according to the Outerbridge classification of osteoarthritis contain anti-Fas IgM antibody as an active ingredient and a pharmaceutically acceptable carrier to alleviate osteoarthritis symptoms by inhibiting the production of cartilage matrix degrading enzymes and by increasing the production of cartilage matrix.

主权项

1. A method of treating patient who suffers from osteoarthritis, comprises
administering to the patient an agent containing an anti-F as IgM antibody as an active ingredient and a pharmaceutically acceptable carrier by means of injection,
wherein the osteoarthritis classified as any of grade 1 to 3 according to the ICRS classification, any of grade 1 to 3 according to the Kellgren-Lawrence classification, or any of grade 1 to 3 according to the Outerbridge classification, andwherein the anti-F as IgM antibody is an agonist antibody against the extracellular domain of a Fas antigen, and wherein the anti-F as IgM antibody is the only active ingredient.