| 发明名称 | Upregulation of rack-1 in melanoma and its use as a marker | ||
| 摘要 | The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocyte cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocyte cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein. | ||
| 申请公布号 | US9201076(B2) | 申请公布日期 | 2015.12.01 |
| 申请号 | US201213730243 | 申请日期 | 2012.12.28 |
| 申请人 | Institut Pasteur;Ecole Nationale Veterinaire D'Alfort;Institut Curie;Centre National de la Recherche Scientifique;Institut National de la Recherche Agronomique (INRA) | 发明人 | Panthier Jean-Jacques;Egidy Giorgia;Sastre-Garau Xavier;Bernex Florence |
| 分类号 | C12Q1/68;G01N33/68;G01N33/574 | 主分类号 | C12Q1/68 |
| 代理机构 | Law Office of Salvatore Arrigo and Scott Lee, LLP | 代理人 | Law Office of Salvatore Arrigo and Scott Lee, LLP |
| 主权项 | 1. A method for detecting the level of expression of RACK-1 mRNA comprising: a) providing a biopsy comprising melanocytes from a human patient; and b) performing an in situ hybridization assay on the biopsy to detect the level of expression of RACK-1 mRNA in the melanocytes. | ||
| 地址 | Paris FR | ||