发明名称 |
THERAPEUTIC AGENT FOR GLAUCOMA AND METHOD FOR PREPARING THE SAME |
摘要 |
The present invention can prevent apoptosis of retinal neuronal cells due to multiple effects by effectively delivering a neuroprotection drug to the retinal neuronal cells and mollifying toxicity of amyloid beta as albumin, a component of a carrier, is combined with the amyloid beta. A therapeutic agent in accordance with the present invention consists of solid albumin nanoparticles, and thus can be effectively delivered to the retinal neuronal cells by intravitreal injection. In addition, the neutoprotection drug carrying the albumin nanoparticles, reaching an inner limiting membrane and a ganglion cell layer is continuously released, thereby decreasing the number of times injecting the drug. |
申请公布号 |
KR101571039(B1) |
申请公布日期 |
2015.11.27 |
申请号 |
KR20140060712 |
申请日期 |
2014.05.21 |
申请人 |
SOGANG UNIVERSITY RESEARCH FOUNDATION;SEOUL NATIONAL UNIVERSITY HOSPITAL;SK TELECOM CO., LTD. |
发明人 |
KIM, HYUN CHEOL;JANG, N SEOK;MOON, HYUNG WON;PARK, KI HO;JEOUNG, JIN WOOK |
分类号 |
A61K47/42;A61K9/16;A61K31/498;A61P27/06 |
主分类号 |
A61K47/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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