| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to paediatric traumatology, and can be used for treating fractures in the children suffering a multisystem injury. The optimal time of osteosynthesis is determined by measuring during the first post-injury hours the blood serum concentrations of S100 protein and cystatin C markers: the reference concentrations of S100 protein 312.2-587.8 ng/l and cystatin C 832.8-1062 ng/ml followed by a two-fold or higher increase for 1-4 days show manifestations of severe cerebral and renal metabolic disturbances; a general therapy is optimised, and a delayed osteosynthesis is performed at least 5-7 days later; the reference concentrations of S100 protein 103.8-292.0 ng/l and cystatin C 541-967 ng/ml followed by at least two-fold increase or decrease during the 1and following days show reversible functional cerebral and renal metabolic disturbances, whereas the 1-4post-injury day is considered to be the optimal time for osteosynthesis.EFFECT: using the method enables detecting latent organ failures, assessing a degree of severity and performing the osteosynthesis as soon as reasonable that is expected to increase the clinical effectiveness in the concomitant and multisystem injury in the children.4 tbl, 8 dwg, 3 ex |
