VEGF ANTAGONIST FORMULATIONS SUITABLE FOR INTRAVITREAL ADMINISTRATION VEGF
摘要
Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has the amino acid sequence showing in SEQ ID No: 4 or amino acids 27-457 of SEQ ID No: 4.
申请公布号
HK1204580(A1)
申请公布日期
2015.11.27
申请号
HK20150105252
申请日期
2015.06.02
申请人
REGENERON PHARMACEUTICALS INC.
发明人
FURFINE, ERIC E;DIX, DANIEL D;GRAHAM, KENNETH, S. KS;FRYE, KELLY K