| 主权项 |
1. A peptide, which comprises an amino acid sequence represented by at least the formula (1), (2) or (3) described below and is composed of 12 to 50 amino acids:
X1-His-X2-X3-Asp-X4-X5-X6-X7-X8-Trp-His (1)(wherein X1 represents Trp or Phe;
X2 represents Leu, Met, Ile or Val; X3 represents Ser, Ala, Thr, Gly, Asn, Asp, Glu, Arg or Lys; X4 represents Leu, Met, Ile, Val, Ala, Phe, Tyr, Trp, His or Cys; X5 represents Trp, Phe or Tyr; X6 represents Gln, Asn, Asp, Glu, Ala, Ser, Thr, Leu, Met, Lys or Arg; X7 represents Asn, Gln, Asp, Glu, Ser, Thr, Ala, Gly, Lys or Arg; and X8 represents Ala, Gly, Ser, Thr, Asn, Val or Cys):
Phe-His-Asp-Trp-X11-Pro-X12-X13-X19-X15-X16-X17 (2) (wherein X11 represents Leu, Met, Ile, Val, Ala, Phe, Tyr, Trp, His or Cys; X12 represents Glu, Asp, Gln, Asn, Ala, Ser, Thr, Lys, Arg or His; X13 represents Val, Ala, Leu, Ile, Met, Thr, Cys or Asn; X14 represents Ser, Ala, Thr, Gly, Asn, Asp, Glu, Arg or Lys; X15 represents Pro, Val, Ile, Lys, Ala, Met, Trp, Tyr, Ser, Thr, Cys or Phe; X16 represents Pro, Val, Ile, Lys, Ala, Met, Trp, Tyr, Ser, Thr, Cys or Phe; and X17 represents Asp, Glu, Asn, Gln, Ala, Ser, Thr, Lys, Arg or His), and
Leu-His-X21-Ser-X22-Trp-Met-X23-X24-X25-X26-X27 (3) (wherein X21 represents Gln, Asn, Asp, Glu, Ala, Ser, Thr, Leu, Met, Lys or Arg; X22 represents Glu, Asp, Gln, Asn, Ala, Ser, Thr, Lys, Arg or His; X23 represents Tyr, Phe, Trp, His, Leu, Met, Ile, Val, Cys or Ala; X24 represents Val, Ala, Leu, Ile, Met, Thr, Cys or Asn; X25 represents Asp, Glu, Asn, Gln, Ala, Ser, Thr, Lys, Arg or His; X26 represents Ile, Val, Leu, Met, Ala, Phe, Tyr, Trp or Gly; and X27 represents His, Tyr, Phe, Lys, Arg, Leu, Met or Ala.) |
