Immunosuppressive polypeptides and nucleic acids

摘要

IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS The invention provides immunosuppressive polypeptides and nucleic acids encoding such polypeptides. In one aspect, the invention provides mutant CTLA-4 polypeptides and 5 nucleic acids encoding mutant CTLA-4 polypeptides. Compositions and methods for utilizing such polypeptides and nucleic acids are also provided.