发明名称 LEUKEMIA THERAPEUTIC AGENT, LEUKEMIA CELL GROWTH INHIBITOR, HEMATOPOIETIC STEM CELL TRANSPLANTATION PRETREATMENT AGENT, AND DETERMINING METHOD OF EFFECT
摘要 PROBLEM TO BE SOLVED: To provide a Leukemia therapeutic agent, Leukemia cell growth inhibitor, hematopoietic stem cell transplantation pretreatment agent, and determining method of effect.SOLUTION: FASN inhibitor is useful as a leukemia therapeutic agent and the like because of an action which inhibits proliferation of leukemia cell having at least either one fusion gene of a NUP98 fusion gene, CALM fusion gene, and AF10 fusion gene. By the leukemia therapeutic agent and the like, it is useful for the treatment of leukemia which has at least either one fusion gene of a NUP98 fusion gene, CALM fusion gene, and AF10 fusion gene, or hematopoietic stem cell transplantation.
申请公布号 JP2015212242(A) 申请公布日期 2015.11.26
申请号 JP20140095467 申请日期 2014.05.02
申请人 NATIONAL CANCER CENTER 发明人 KITABAYASHI KAZUO;SHIMA YUTAKA
分类号 A61K45/00;A61K31/198;A61K31/365;A61K31/675;A61K31/704;A61K31/7048;A61K31/7068;A61K31/7105;A61K31/713;A61K33/24;A61K45/06;A61P35/02;C12Q1/25;C12Q1/68 主分类号 A61K45/00
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