| 发明名称 |
Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof |
| 摘要 |
The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal. The presently described methods are carried out by comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride. The composition has reduced side effects when compared with unconjugated hydrocodone. |
| 申请公布号 |
US2015335759(A1) |
申请公布日期 |
2015.11.26 |
| 申请号 |
US201514816915 |
申请日期 |
2015.08.03 |
| 申请人 |
KemPharm, Inc. |
发明人 |
Mickle Travis;Guenther Sven;Mickle Christal;Chi Guochen;Kanski Jaroslaw;Martin Andrea K.;Bera Bindu |
| 分类号 |
A61K47/48;A61K31/485;A61K31/167 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride wherein the composition has reduced side effects when compared with unconjugated hydrocodone. |
| 地址 |
Coralville IA US |
