RETRO-INVERSO ANALOGS OF SPADIN DISPLAY INCREASED ANTIDEPRESSANT EFFECTS
摘要
Compositions, pharmaceutical compositions and biodegradable pharmaceutical compositions containing at least one analog of spadin or at least one analog of a propeptides of spadin or mixtures thereof are described. Methods for treating depression using the analogs of spadin or analogs of propeptides of spadin or mixtures thereof, as well as methods for blocking TREK-1 channel activity are also disclosed.
申请公布号
WO2015110915(A3)
申请公布日期
2015.11.26
申请号
WO2015IB00338
申请日期
2015.01.27
申请人
MEDINCELL;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人
GAUDRIAULT, GEORGES;HEURTEAUX, CATHERINE;MAZELLA, JEAN;BORSOTTO, MARC;MOHA OU MAATI, HAMID;VEYSSIERE, JULIE