发明名称 |
COMPOSITION OF EXTERNAL APPLICATION TO SKIN |
摘要 |
The composition of external application to the skin according to the present invention may specifically control the relative amount between long-chain amides and sterols and the relative amount between lipid components and an emulsifier in the emulsion having a multi-layered lamella structure, the emulsion comprising a relatively larger content of dermatologically useful hydrophobic material in a formulation. Thus, the formulation having significantly high stability and excellent characteristics can be obtained in spite of the high content in the lipid components and the emulsifier. |
申请公布号 |
US2015335756(A1) |
申请公布日期 |
2015.11.26 |
申请号 |
US201314647395 |
申请日期 |
2013.11.29 |
申请人 |
NEOPHARM CO., LTD. |
发明人 |
LEE Shin-Hee;KIM Yoon;KIM Su-Hwan;Park Byeong-Deog |
分类号 |
A61K47/44;A61K9/00;A61K47/18;A61K9/107;A61K47/10 |
主分类号 |
A61K47/44 |
代理机构 |
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代理人 |
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主权项 |
1. A multi-lamellar emulsion type composition for skin external application, which comprises:
15-22 wt % of lipid components comprising, based on the total weight of the composition, 3-4 wt % of long-chain amide and sterol and 12-18 wt % of fatty acid and fatty alcohol; 6-10 wt % of an emulsifier; 12-18 wt % of oil; and a balance of purified water, wherein the ratio of the content of the long-chain amide to that of the sterol is 0.1-1.8:1 by weight, the ratio of the content of the lipid components to the emulsifier is 1.8-3.0:1 by weight, and the sum of the contents of the lipid components and the emulsifier is 21-32 wt % based on the total weight of the composition. |
地址 |
Daejeon KR |