| 摘要 |
The present invention relates to a composition for enhancing immunity and, more specifically, to a pharmaceutical composition, a food composition, a healthy food, and a feed additive for enhancing immunity containing an extract of Apios americana Medikus or a fermented extract of Apios americana Medikus as an active ingredient. The extract of Apios americana Medikus or the fermented extract of Apios americana Medikus in the present invention promotes production of immune enhancers such as NO, TNF-α, IL-1β, and IL-6 by increasing expression of genes or proteins thereof in a macrophage Raw 264.7 cell line, and boosts proliferation of mouse spleen cells and proliferation of T-lymphocytes and B-lymphocytes in the mouse spleen, thereby being useful as a drug and an additive for food or feed effective in enhancing immunity. Particularly, as the extract of Apios americana Medikus or the fermented extract of Apios americana Medikus in the present invention is a safe ingredient derived from a natural substance, the composition of the present invention containing the extract as an active ingredient is safe for a human body without side effects even for a long term use. |
