发明名称 |
TREATMENT AND PROGNOSIS OF LYMPHANGIOLEIOMYOMATOSIS |
摘要 |
Embodiments disclosed herein relate to treatment methods, diagnosis methods, drug efficacy evaluation methods and prognosis evaluation methods of lymphangioleiomyomatosis (LAM) and a disease associated with a mutation in a tuberous sclerosis complex (TSC) gene. The methods comprising analyses of the levels of lysophosphatidylcholine (LPC) in a biological sample of a subject, or comprising analyses of images of the location and signal intensity of isotope-labeled choline in the subject. |
申请公布号 |
US2015338425(A1) |
申请公布日期 |
2015.11.26 |
申请号 |
US201214357648 |
申请日期 |
2012.11.14 |
申请人 |
THE BROAD INSTITUTE, INC. ;THE BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
HENSKE Elizabeth;Clary CLISH;PRIOLO Carmen |
分类号 |
G01N33/92;A61K51/00;A61K31/517;A61K31/4045;A61K31/5377;A61K31/513 |
主分类号 |
G01N33/92 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Cambridge MA US |