发明名称 TREATMENT AND PROGNOSIS OF LYMPHANGIOLEIOMYOMATOSIS
摘要 Embodiments disclosed herein relate to treatment methods, diagnosis methods, drug efficacy evaluation methods and prognosis evaluation methods of lymphangioleiomyomatosis (LAM) and a disease associated with a mutation in a tuberous sclerosis complex (TSC) gene. The methods comprising analyses of the levels of lysophosphatidylcholine (LPC) in a biological sample of a subject, or comprising analyses of images of the location and signal intensity of isotope-labeled choline in the subject.
申请公布号 US2015338425(A1) 申请公布日期 2015.11.26
申请号 US201214357648 申请日期 2012.11.14
申请人 THE BROAD INSTITUTE, INC. ;THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 发明人 HENSKE Elizabeth;Clary CLISH;PRIOLO Carmen
分类号 G01N33/92;A61K51/00;A61K31/517;A61K31/4045;A61K31/5377;A61K31/513 主分类号 G01N33/92
代理机构 代理人
主权项
地址 Cambridge MA US