发明名称 |
ENGINEERED TISSUE CONSTRUCTS |
摘要 |
A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate. |
申请公布号 |
WO2015134999(A3) |
申请公布日期 |
2015.11.26 |
申请号 |
WO2015US19541 |
申请日期 |
2015.03.09 |
申请人 |
CASE WESTERN RESERVE UNIVERSITY;WORCESTER POLYTECHNIC INSTITUTE |
发明人 |
ALSBERG, EBEN;DIKINA, ANNA D.;ROLLE, MARSHA W. |
分类号 |
C12N5/00;A61F2/20;C12N5/02 |
主分类号 |
C12N5/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|