发明名称 |
N-ACYLETHANOLAMINE HYDROLYZING ACID AMIDASE (NAAA) INHIBITORS AND THEIR USE THEREOF |
摘要 |
A compound is represented as Formula I, a tautomer thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. Compounds of Formula I are inhibitors of N-acylethanolamine hydrolyzing acid amidase (NAAA). The present technology is directed to compounds, compositions, and methods to inhibit N-acylethanolamine hydrolyzing acid amidase and to treat N-acylethanolamine hydrolyzing acid amidase mediated conditions in a subject. |
申请公布号 |
WO2015179190(A1) |
申请公布日期 |
2015.11.26 |
申请号 |
WO2015US30583 |
申请日期 |
2015.05.13 |
申请人 |
NORTHEASTERN UNIVERSITY |
发明人 |
MALAMAS, MICHAEL;MAKRIYANNIS, ALEXANDROS;SUBRAMANIAN, KUMARA VADIVEL;WHITTEN, KYLE M.;ZVONOK, NIKOLAI M.;WEST, JAY MATTHEW;MCCORMACK, MICHAEL;PAVLOPOULOS, SPIRO |
分类号 |
A61K31/26 |
主分类号 |
A61K31/26 |
代理机构 |
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代理人 |
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