发明名称 |
EXOSOME AND LIPID BIOMARKERS FOR MEMORY LOSS |
摘要 |
The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one sample from the subject to determine a value of the subject's exosomal profile or combined biomarker profile (lipids plus exosomal cargo) and comparing the value of the subject's exosomal or combined biomarker profile with the value of a normal exosomal or biomarker profile, respectively. A change in the value of the subject's exosomal or combined biomarker profile, including a change in the subject's exosomal or combined biomarker profile, over normal values is indicative that the subject has an increased risk of suffering from memory impairment compared to a normal individual. |
申请公布号 |
WO2015179875(A1) |
申请公布日期 |
2015.11.26 |
申请号 |
WO2015US32490 |
申请日期 |
2015.05.26 |
申请人 |
GEORGETOWN UNIVERSITY;UNIVERSITY OF ROCHESTER |
发明人 |
FIANDACA, MASSIMO S.;MAPSTONE, MARK E.;FEDEROFF, HOWARD J. |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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