发明名称 |
METHOD FOR EDITING A GENETIC SEQUENCE |
摘要 |
This disclosure describes methods, polynucleotides, cells, compositions, and treatment methods that involve changing a genomic nucleotide sequence. Generally, the method includes introducing a donor polynucleotide and a nucleotide that encodes an enzyme that cuts at least one strand of DNA into a cell that has a genomic sequence in need of editing, allowing the enzyme to cut at least one strand of the genomic sequence, and allowing the donor sequence to replace the genomic sequence in need of editing. |
申请公布号 |
CA2949697(A1) |
申请公布日期 |
2015.11.26 |
申请号 |
CA20152949697 |
申请日期 |
2015.05.20 |
申请人 |
REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
TOLAR, JAKUB;BLAZAR, BRUCE ROBERT;VOYTAS, DANIEL FRANCIS;OSBORN, MARK JOHN |
分类号 |
C12N15/85;C12N5/10;C12N9/22;C12N15/00;C12N15/09;C12N15/56;C12N15/90 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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