| 摘要 |
<p>A silicon particle comprising a silicon body, a functionalized silica surface surrounding the silicon body, and a targeting moiety specifically targeting tumor cells, and, optionally, an enzymatically metabolizable compound, is useful in the treatment of cancer by producing cell death after particle internalization.</p> |
| 申请人 |
UNIVERSITAT ROVIRA I VIRGILI;FUNDACIO CENTRE TECNOLOGIC DE LA QUIMICA DE CATALUNYA;INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS(ICREA);UNIVERSITAT POLITÈCNICA DE VALÈNCIA;CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS;UNIVERSIDAD DE VIGO;FUNDACIÓN HOSPITAL DE MADRID;PHILIPPS UNIVERSITÄT MARBURG;MEDCOMTECH, S.A. |
发明人 |
ÁLVAREZ PUEBLA, RAMÓN ÁNGEL;FENOLLOSA ESTEVE, ROBERTO;MESSEGUER RICO, FRANCISCO JAVIER;RODRIGUEZ, MARIE ISABELLE;ÁLVAREZ RODRIGUEZ, ROSANA;RODRIGUEZ DE LERA, ÁNGEL;GARCIA-RICO FERNÁNDEZ, EDUARDO;YU, XIANG;CARREGAL ROMERO, SUSANA;PARAK, WOLFGANG JOHANN;VILLANUEVA LEAL, CARLOS;RIVERA GIL, PILAR;ÁLVAREZ RODRIGUEZ, SUSANA |
