发明名称 |
GREMLIN-1 ANTIBODY |
摘要 |
The present invention relates to a Gremlin-1 antibody that inhibits Gremlin-1 in a manner independent of bone morphogenetic protein (BMP) or vascular endothelial growth factor receptor-2 (VEGFR-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on Gremlin-1, and therefore, can be effectively used in treating cancer or immune disease. |
申请公布号 |
EP2826790(A4) |
申请公布日期 |
2015.11.25 |
申请号 |
EP20130760897 |
申请日期 |
2013.03.15 |
申请人 |
SNU R&DB FOUNDATION;KIM, HYUN-KEE |
发明人 |
KIM, HYUN KEE;CHUNG, JUNHO;KIM, MIN SOO;YOON, SOO MIN |
分类号 |
C07K16/18;A61K39/395;A61P35/00;G01N33/53 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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