发明名称 GREMLIN-1 ANTIBODY
摘要 The present invention relates to a Gremlin-1 antibody that inhibits Gremlin-1 in a manner independent of bone morphogenetic protein (BMP) or vascular endothelial growth factor receptor-2 (VEGFR-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on Gremlin-1, and therefore, can be effectively used in treating cancer or immune disease.
申请公布号 EP2826790(A4) 申请公布日期 2015.11.25
申请号 EP20130760897 申请日期 2013.03.15
申请人 SNU R&DB FOUNDATION;KIM, HYUN-KEE 发明人 KIM, HYUN KEE;CHUNG, JUNHO;KIM, MIN SOO;YOON, SOO MIN
分类号 C07K16/18;A61K39/395;A61P35/00;G01N33/53 主分类号 C07K16/18
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