Immunoglobulin frameworks which demonstrate enhanced stability in the intracellular environment and methods of identifying same
摘要
A single chain variable framework has been selected for intracellular performance which may be used in diagnostic and therapeutic applications, target validation and gene therapy.
申请公布号
EP2947095(A1)
申请公布日期
2015.11.25
申请号
EP20150160739
申请日期
2003.05.21
申请人
ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC
发明人
TISSOT, KATHRIN;EWERT, STEFAN;AUF DER MAUR, ADRIAN;BARBERIS, ALCIDE;ESCHER, DOMINIK