发明名称 |
ACYLGUANIDINES FOR TREATING OSTEOARTHRITIS |
摘要 |
The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia. |
申请公布号 |
EP2945929(A1) |
申请公布日期 |
2015.11.25 |
申请号 |
EP20130811126 |
申请日期 |
2013.12.16 |
申请人 |
MERCK PATENT GMBH |
发明人 |
TSAKLAKIDIS, CHRISTOS;KLEIN, MARKUS;CZODROWSKI, PAUL |
分类号 |
C07C279/20;A61K31/155;A61P5/28;A61P19/02;C07C279/22;C07C311/08;C07C311/16;C07C311/37;C07D233/61;C07D309/14;C07D317/58;C07D317/60;C07D333/20;C07D333/28;C07D335/02 |
主分类号 |
C07C279/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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