发明名称 |
METHOD FOR DETERMINATION OF AGGREGATES |
摘要 |
A method of determining aggregates of a macromolecule monomer in a fluid containing the macromolecule, comprises the steps of: contacting a sample of the fluid with a sensing surface of an interaction analysis sensor, wherein the sensing surface is capable of specific binding interaction with the macromolecule, determining at least one kinetic parameter for the interaction of the fluid sample with the sensing surface, comparing the determined kinetic parameter or parameters with that or those determined for at least one fluid sample having a known fraction or fractions of aggregates of the macromolecule, and determining therefrom the fraction of macromolecule in the sample that is in the form of aggregate or aggregates. |
申请公布号 |
EP2529234(B1) |
申请公布日期 |
2015.11.25 |
申请号 |
EP20110737368 |
申请日期 |
2011.01.27 |
申请人 |
GE HEALTHCARE BIO-SCIENCES AB |
发明人 |
LÖFÅS, STEFAN;PERSSON, BJÖRN |
分类号 |
G01N33/68;G01N33/543;G01N33/557 |
主分类号 |
G01N33/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|